We turn advanced science into therapeutic reality

Our Team

AlphaOnco (formerly Nanobacterie) is the result of over 15 years of pioneering research led by Dr. Edouard Alphandéry.

Leadership & Managing team

Medical and Scientific advice

Eric Barret, Md.
Urological surgeon at the IMM (Institut Mutualiste Montsouris)

Company History

AlphaOnco, previously Nanobacterie, has built a solid foundation to support its long-term growth and clinical ambitions.

Our objective : implement repeated hyperthermia to treat solid tumors. From a bactery with magnetic properties to injectable safe magnetosomes. We tested multiple methods to apply hyperthermia inside solid tumor for a safe solid tumor cancer treatement.

Injectable Magnetosomes -> Device improvement -> Repeated hyperthermia setings
Explore our science
Consult our previous website

Evolution of our products and treatment

✓ Chains of magnetosomes as medical device

Patented

✓ Proof of concept of the treatment of mice bearing breast tumors administered with magnetosomes and whose tumors were heated with an alternating magnetic field, leading to full tumor disappearance in some mice, published.
✓ Chelating agents to stimulate magnetosome production

Patented

✓ Non-pyrogenic magnetosomes stabilized with coating

Patented

Proof of concept of the treatment of mice bearing glioblastoma tumors administered with magnetosomes and whose tumors were heated repeatedly with an alternating magnetic field, leading to full tumor disappearance under optimal conditions, published.
✓ Proof of concept of the treatment of a dog suffering from a large knee sarcoma receiving magnetosomes and whose tumors was heated with ultrasound, leading to a large reduction in tumor volume.
✓ A method to fabricate pure magnetosomes in iron by using a minimal growth medium

Patented

✓ A method to purify magnetosomes through combustion

Patented

✓ A method to maintain the chain arrangement of magnetosomes after lyophilization using a magnetosome formulation containing a cryo-protectant

Patented

✓ Proof of concept of the treatment of mice bearing prostate tumors injected with magnetosomes and heated repeatedly with ultrasound, leading to full tumor disappearance in all treated mice, published.

Our Partners

We favor collaboration between AlphaOnco and other SME or Universities in France and within the European Union.

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