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Olivier Seksek

Senior Researcher CNRS

Magnetosomes coating and formulation

Hyperthermia treatment on cells and small animals combining magnetosomes and various energy sources (Magnetic alternating field, laser, ultrasound, cryotherapy)

Related AlphaOnco publications

Full Disappearance of PC3-Luc Prostate Tumors Mediated by Hyperthermia Under Low Intensity Ultrasound Application in the Presence of Magnetosomes
Pre-clinical proof of concept of AlphaOnco’s treatment on prostate tumors
Cynthia El Hedjaj, Eric Barret, Imène Chebbi, Raphaël Le Fèvre, Caroline Maake, Franco Guscetti, François Guyot, Jean-Francois Aubry, Olivier Seksek, Edouard Alphandéry. Advanced Therapeutics. Volume 8, Issue 2, February 2025.
Prostate Cancer
Biocompatibility, Magnetosomes based products, Preclinical studies, Treatment method
Publication
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Nanoprobe Synthesized by Magnetotactic Bacteria, Detecting Fluorescence Variations under Dissociation of Rhodamine B from Magnetosomes following Temperature, pH Changes, or the Application of Radiation
Article presenting a method to detect magnetosomes through a fluorescence de-quenching mechanism.
Edouard Alphandéry, Darine Abi Haidar, Olivier Seksek, Maxime Thoreau, Alain Trautmann, Nadege Bercovici, Florence Gazeau, François Guyot, Imène Chebbi. ACS Appl. Mater. Interfaces 2017, 9, 42, 36561–36572.
Magnetosomes based products, R&D
Publication
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Biocompatible coated magnetosome minerals with various organization and cellular interaction properties induce cytotoxicity towards RG-2 and GL-261 glioma cells in the presence of an alternating magnetic field
Article presenting the preparation and characterization of magnetosomes coated with chitosan, neridronate, and PEI.
Yasmina Hamdous, Imène Chebbi, Chalani Mandawala, Raphael Le Fèvre, François Guyot, Olivier Seksek & Edouard Alphandéry. Journal of Nanobiotechnology volume 15, Article number: 74 (2017).
Glioblastoma
Magnetosomes based products, R&D
Publication
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